In practice, every situation is offense vs defense, Rides vs Clears, Man up vs man down.  In practice, player become so accustomed to playing against their counterpart that they game plan specifically in practice for how to win each possession.  I have noticed that often times teams become so caught up on beating their own team during practice, that when the real opponent shows them a look they are not as used to playing against, they panic.  It is imperative that as a season progresses, your team must know how to run your rides, clears, set offenses and defenses against any look.  No matter what offensive set, or what man or zone package a team throws, a team should never get uncomfortable facing something new.  Overall, make sure your team practices against different looks, so they do not become accustomed to playing against the same strategies over and over.